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25 Cards in this Set
- Front
- Back
True or False
1)Small Uncharged molecules can transverse the membrane easily by diffusion? |
True
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What are the 3 types of Sphingolipids that exist?
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1) Ceramides
2) Cerebrosides 3) Gangliosides |
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Sphingolipids are built one of two amino acids, what are they ?
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1) Shingosine
2) Dihydroxysphingosine |
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Name 2 Major functions of the cell membrane
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1) Communication
2) SELECTIVE permeability Barrier |
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Cell Membranes contain _________ receptors on their surface that specifically bind to Hormones and Nuerotransmitters?
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Glycoproteins!!
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What are the 4 membrane functions mentioned in the text?
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1) Catalysis
2) Transport 3)Structural 4) Signal Recognition |
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True or False?
Membranes comprimise approximately 75% of the average prokaryotic cell by weight ? |
False
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Biological Membrane vary in thickness between ___ and ____ nm's?
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5 - 10 nm
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The presence of lipids in biological membranes was first established by what scientist?
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Charles Overton in 1899
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What two dutch scientist studied RBC's and extracted their membranes to coin term "bi-layer" ?
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Gorter and Grendel (1925)
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All of the following are components of the prokaryotic membrane except?
a) Phospholipids b) Proteins c) Cholesterol d) Carbohydrates |
Cholesterol!!
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True or false?
Several antibiotics selectively target bacterial cells that have cholesterol, while not affecting host cell that lack cholesterol?? |
FALSE!!! (Pg 211 of your notes)
Antibiotics SELECTIVELY target cells LACKING cholesterol while not affecting host cells that are cholesterol rich |
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What two scientist proposed the "fluid Mosiac Model?"
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Singer and Nicolson (1972)
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Protein migration has been studied using what technique in which mouse and human cells are fused?
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CELL FUSION TECHNIQUES
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Water is able to cross the biological membrane through what trans membrane channels?
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AQUAPORINS!
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True or False?
Mediated Transport may use PASSIVE transport? |
True. Only when the biological molecules are moving AGAINST their concentration gradient is when ATP is required.
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True or false
Ectoenzymes have gtheir active sites facing the cell interior ? |
False,
Ectoenzyme = Active site facing the outside of the cell Endoenzyme = Active site facing the cell interior |
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Classical G- Receptor Proteins possess ___ transmembrane regions and are termed _____
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Classical G Receptor Proteins posses seven transmembrane regions and are termed serpentine
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True or False
G Proteins may stimulate and inhibit adenylate cyclase activity? |
True
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Additional trimeric G proteins have been identified in brain neurons (Go), in smooth muscle of blood vessels (Gq or Gp), in olfactory sensory neurons (Golf)...Do these G proteins have an effect on adenylate cylcase? If not, how do these G proteins function?
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No, These special G proteins work by altering phospholipase C activity on the Beta subunit
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IN the resting cell, the G protein normally lies adjacent to the cell receptor in an inactive, off state, binding to what molecule?
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GDP, since its inactive
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The most well documented monomeric G protein is the product of the _____ gene?
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ras gene (also known as Ras.)
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Myelin Sheath is ____% lipid
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Myelin Sheath is 75% Lipid
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The inner mitochondrial membrane is ___ % protein
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IMM is 80% protein
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In order to flip from the outer leaflet to the inner leaflet , the phospholipid would have to cross into the inner hydrophobic enviroment using what energy yeilding enzyme?
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Flippases
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