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93 Cards in this Set

  • Front
  • Back

Membrane phospholipids associate to form bilayers T/F

True

Membrane phospholipids have hydrophobic tails and hydrophilic heads T/F

True

Membrane phospholipids give the membrane fluidity T/F

True

Membrane phospholipids readily flip-flop from one side of the membrane to the other T/F

False

The main difference between a cell that responds to a signal and the one that does not is the presence of a

receptor

The signals that bind to receptors of the same cell that made them are known as

autocrine signals

The general name for an enzyme that transfers phosphate groups from ATP to a protein is

protein kinase

Which of the following is NOT a membrane receptor

cortisol receptor

Which of the following is NOT a second messenger

ATP

A researcher treats cells with a chemical that prevents DNA synthesis from starting. This treatment would trap the cells in which part of the cell cycle?

G1

The restriction point is

G1-to-S transition

Plasmodesmata are most similar in function to which of the following structures in animal cells?

gap junctions

Biological membranes are composed of

lipids, proteins and carbohydrates

Which ofthe following includes all the others?

passive transport

Anartificial cell consisting of an aqueous solution enclosed in a selectively permeable membrane is immersed in a beaker containing a different solution.




Initially, the solution outside the cell is____ to the cell

hypotonic

Knowledge of the cell cycle has led to improved means of treating cancer. The drug 5-fluorouracil blocks the synthesis of thymine. This drugs inhibits the cell cycle at the end of

G1

A deer smells a predator as it passes by and quickly bounds to safety. Which of the following represents the correct order of steps in the olfactory signal transduction pathway that is involved?a. Receptor binds signal, conformational change occurs in signal, signal travels to target cell, signal is transduced within the cell, effects from the signal transduction occur

Signaltravels to target cell, receptor binds signal, conformational change occurs inreceptor, signal is transduced within the cell, effects from the signaltransduction occur

__________ is an enzyme that converts ATP to cAMP?

Adenylyl cyclase

You view an animal cell through a microscope and observe dense, duplicated chromosomes scattered throughout the cell. Which state of mitosis are you looking at?

prophase

______is the region on a duplicated chromosome that holds the sister chromatids together?

centromere

Nucleosomes

consist of DNA wound around a histone core

Which of the following phases of the cell cycle is NOT part of interphase?

M

The general structure of biological membranes is known as the ________?

fluid mosaic model

animal cell membranes may be up to ________ cholesterol

25%

What membrane proteins lack exposed hydrophobic groups and don't penetrate the bilayer?

Peripheral membrane proteins

What membrane proteins have hydrophobic and hydrophilic regions and domains?

Integral membrane proteins

What is the technique that reveals proteins embedded in the phospholipid bilayers of cellular membranes?

Freeze-fracturing

________________ extend all the way through the phospholipid bilayer

transmembrane proteins

Glycolipids have what ?

carbohydrate + lipid

Glycoproteins have what?

carbohydrate + protein

What is the same molecule sticks out from both cells and forms a bond?

homotypic

The cells have different proteins is what?

heterotypic

___________ help ensure directional movement of materials.

tight junctions

Desmosomes are like what?

spot welds

___________ allow communication

gap junction

What protein binds to the matrix outside epithelial cells and non covalent?

integrin

Some substances can pass through but not others is what?

selective permeability

No outside energy required (diffusion)

passive transport

Energy required is what?

active transport

the difference in concentration between one side of the membrane andthe other.

concentration gradient

The process of random movement toward equilibrium

diffusion

Diffusion rate depends on what ?

diameter of molecules, temperature, and concentration gradient

Small molecules pass through the lipid bilayer

simple diffusion

The diffusion of water

osmosis

Higher solute concentration

hypertonic

Equal solute concentration

isotonic

lower solute concentration

hypotonic

Plant cells with rigid cell wallsbuild up internal pressure that keeps more water from entering

turgor pressure

No cellular energy is required but cellular protein(s) and a concentration gradient are necessary

Passive

Integral membrane proteins that form a channel.

Channel proteins

Membrane proteins that bind some substances and speed their diffusion through the bilayer

Carrier proteins

Specific channel proteins with hydrophilic pores

ion channels

How does an ion channel allow one ion to pass through but not another?

Its not a matter of size or charge of ion

Water can cross a membrane by ‘hitchhiking’ with ions, or moving through special water channels called

aquaporins

What transports polar molecules such as glucose across membranes in both directions.

carrier proteins

The facilitated diffusion system is said to be

saturated

What protein moves one substance in one direction?

uniporter

What protein moves two substances in one direction?

Symporter

What protein moves two substances in opposite directions?

Antiporter

Symporters and anti porters are also called what and why?

Coupled transporters because they move two substances at once

What requires direct hydrolysis of ATP?

primary active transport

What is it when energy comes from an ion concentration gradient that is established by primary active transport?

secondary active transport

What is a primary active transport?

The sodium–potassium (Na+–K+) pump (an antiporter)

Where is the Na+- K+ pump found?

animal cells

Macromolecules can be taken in or secreted by means of what?

Membrane vesicles

What processes that brings molecules and cells into a eukaryotic cell?

Endocytosis

What process is when molecules or entire cells areengulfed?

phagocytosis

What process is when a vesicle forms to bring small dissolved substances or fluids into a cell and constant in endothelial cells?

Pinocytosis

What process is when material in vesicles is expelled from a cell?

Exocytosis

What is the sequence of events that lead to a cell's response to a signal?

Signal transduction pathway

What signals affect the cells that made them?

Autocrine

What signals affect only adjacent cells.

Juxtacrine

What signals affect nearby cells?

Paracrine

What does a signal transduction pathway involve?

signal, receptor and responses

What is signal transduction pathways can be interrelated?

crosstalk

Receptor proteins have very specific binding sites for what?

ligands

What else can bind to receptor proteins?

inhibitors or antagonists

Where can receptors be located

cytoplasm or cell membrane

What receptors are small or non polar ligands that can diffuse across the cell membrane?

intracellular receptors

What receptors are large or polar ligands that bind to cell membrane receptors?

Membrane receptors

What are channel proteins that allow ions to enter or leave a cell?

ion channel receptors

What receptor is a gated ion channel?

acetylcholine receptor

What receptor catalyzes phosphorylation of themselves and/or other proteins? Ex: insulin

Protein kinase receptor

What receptor has ligand binding change the shape of the cytoplasmic region, which binds to a G protein?

G protein-linked receptor

What protein binds GDP and GTP, receptor and effector?

G proteins

Where are intracellular receptors located and what do they do?

Inside the cell (cytoplasm or nucleus) and they respond to physical signals such as light or chemicals

What small nonprotein molecules can diffuse through the cytoplasm and mediate further steps in pathways?

second messengers

Protein kinase receptors bind signals called what?

growth factors

What is a pathway in which one protein kinase activates the next by phosphorylation ?

protein kinase cascade

What later removes the phosphate allowing the pathways to reset?

phosphate enzymes

In protein kinase cascade , the signal is what?

amplified at each step

What are the factors that influence the degree of fluidity of membranes?

temperature and lipid composition

What happens to animal cells in a hypotonic solution?

they burst