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Definisi kolelitiasis

Deposit kristal empedu (kolesterol atau pigmen) yang ditemukan di dalam kantung empedu

Patogenesis kolelitiasis

Batu empedu terbentuk akibat ketidakseimbangan faktor pronukleasi dengan faktor anti nukleasi.



- faktor pronukleasi: kolesterol, glikoprotein mukus


- faktor antinukleasi: garam empedu, lesitin

Manifestasi klinis

Kolik bilier, yaitu:


- nyeri kuadran kanan atas


- kadang menjalar ke skapula atau bahu kanan


- episodik, remitten, mendadak


- berlangsung 15 menit - 5 jam


- hilang perlahan dengan sendirinya


- disertai mual


- dicetuskan makanan berlemak

Penegakkan diagnosa

USG > accoustic shadow

Tata laksana kolelitiasis

- asam ursodeksikolat


- kolesistektomi laparoskopi


- ERCP

Komplikasi kolelitiasis

- kolesistitis akut


- koledokolitiasis


- kolangitis


- pankreatitis akut

Sumber utama:


Kapita Selekta Kedokteran edisi IV

Arespulsa FK UMY 2013