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99 Cards in this Set
- Front
- Back
Chlorpromazine |
Typical Anti psychotic Phentothiazine Derivative D2>5-HT2A |
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Thioridazine |
Typical Anti psychotic Phentothiazine Derivative D2>5-HT2A |
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Triflouperazine |
Typical Anti psychotic Phentothiazine Derivative D2>5-HT2A |
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Perphenazine |
Typical Anti psychotic Phentothiazine Derivative D2>5-HT2A |
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Fluphenazine |
Typical Anti psychotic Phentothiazine Derivative D2>5-HT2A |
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Thiothixene |
Typical Anti psychotic Thioxanthene Derivative D2>5-HT2A |
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Chlorprothixene |
Typical Anti psychotic Thioxanthene Derivative D2>5-HT2A |
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Haloperidol |
Typical Anti psychotic Butyrophenone Derivative D2>5-HT2A |
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Droperidol |
Typical Anti psychotic Butyrophenone Derivative D2>5-HT2A |
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Spiroperidol |
Typical Anti psychotic Butyrophenone Derivative D2>5-HT2A |
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Pimozide |
Typical Anti psychotic Miscellaneous Derivative D2>5-HT2A |
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Molindone |
Typical Anti psychotic Miscellaneous Derivative D2>5-HT2A |
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Clozapine |
Atypical Anti psychotic Agranulocytosis D4=Alpha-1>5HT2A>D2=D1 |
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Risperidone |
Atypical Anti psychotic D2=5HT2A Not as effective |
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Olanzapine |
Atypical Anti psychotic 5HT2A>H1>D4>D2>Alpha-1>D1 Weight gain |
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Quetiapine |
Atypical Anti psychotic H1>Alpha-1>D2>5-HT2A |
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Ziprasidone |
Atypical Anti psychotic 5-HT2A=D2 Cardiac problems |
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Aripiprazole |
Atypical Anti psychotic D2=5-HT2A>D4>Alpha-1=H1>>D1 Partial Agonist |
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Asenapine |
Atypical Anti psychotic D2=5-HT2A Sublingual |
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Lurasidone |
Atypical Anti psychotic D2=5-HT2A=5-HT7 |
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Levodopa (L-DOPA) |
Parkinson's Treatment Carbidopa Effects - Nausea - Heart issues - Behavorial Limitations - Loss of response -Involuntary movements -Freezing episodes -On-off fluctuations |
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Selegiline |
Parkinson's Treatment MAO-B inhibitor Prolongs effect of L-DOPA |
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Rasagiline |
Parkinson's Treatment Selective, inhibitor MAO-B inhibitor Used early on, later with L-DOPA |
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Tolcapone |
Parkinson's Treatment Selective COMT inhibitor Inhibits L-DOPA metabolism outside of the brain Hepatic injury and liver failure |
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Entacapone |
Parkinson's Treatment Inhibits L-DOPA metabolism outside of brain No hepatoxicity |
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Bromocriptine |
Parkinson's Treatment D2 Selective Agonist Used with long term DOPA Side effects similar to L-DOPA |
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Pergolide |
Parkinson's Treatment D1 and D2 agonist Similar to L-DOPA Heart valve damage |
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Pramipexole |
Parkinson's Treatment D2 Agonist Non-ergot Used in restless legs syndrome |
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Ropinirole |
Parkinson's Treatment D2 Agonist Non-ergot Used in restless legs syndrome |
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Rotigotine |
Parkinson's Treatment D3/D2/D1 Agonist Non-ergot Transdermal |
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Anticholinergic Drugs |
Benzotropine mesylate Trihexyphenidyl Procyclidine Diphenhydramine Blocks effects of ACh restoring balance of DA and ACh Early stages |
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Amantadine |
Antiviral Increases DA synthesis Worse than L-DOPA but better than ACh Early on |
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Nitrous Oxide |
General Anesthetic Low potency Low solubility Gas |
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Cyclopropane |
General Anesthetic Gas High potency Cardiac problems |
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Diethyl ether |
General Anesthetic Liquid Potent |
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Halothane |
General Anesthetic Liquid Potent Corrosive Can't really use with epinephrine Hepatoxicity |
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Methoxyflurane |
General Anesthetic Liquid Most potent Labor |
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Enflurane |
General Anesthetic Liquid Dissolves rubber |
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Isoflurane |
General Anesthetic Liquid Most extensively used |
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Desflurane |
General Anesthetic Liquid |
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Sevoflurane |
General Anesthetic Liquid |
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Methohexital Sodium |
General Anesthetic IV Barbiturate Poor analgesic Little Muscle Relaxation Cardio Effects Respiratory Effects Used before analgesics |
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Thiopental sodium |
General Anesthetic IV Barbiturate Poor analgesic Little Muscle Relaxation Cardio Effects Respiratory Effects Used before analgesics |
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Opioids used as anesthetics |
Fentanyl Alfentanil Sufentanil Remifentanil IV Extremely potent |
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Ketamine |
General Anesthetic IV Trance like state No muscle relaxation Hallucinations |
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Propofol |
General Anesthetic IV New widely used |
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Tricyclic Drugs (10 of them) |
Immediately A Tough Dreamy Dancer Neutralized Paranoid Clean Action Men Imipramine Amitriptyline Trimipramine Doxepin Desipramine Nortriptyline Protriptyline Clomipramine Amoxapine Maprotiline |
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Trazodone |
Atypical Second Generation Antidepressant 5-HT2A Blocker Sedative Priapism |
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Nefazodone |
Atypical Second Generation Antidepressant 5-HT2A Blocker Hepatoxicity |
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Mirtazapine |
Atypical Second Generation Antidepressant Alpha-2 Adrenergic Blocker among others Minor side effects Agranulocystosis |
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Bupropion |
Atypical Second Generation Antidepressants Smoking cessation Mechanism uncertain Seizures |
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SSRI's (9 of them) |
For Sam's Pie Fred Vacuumed Dirty Closets Every Day Fluoxetine Sertraline Paroxetine Fluvoxamine Venlafaxine Desvenlafaxine Citalopram Escitalopram Duloxetine |
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MAO inhibitors |
Antidepressants Tranylcypromine Phenelzine Isocarboxazid Tyramine food sensitivity |
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Lithium Salts |
Used to treat bipolar disorder Stabilizes mood Lithium toxicity |
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Valproic Acid |
Anticonvulsant/Bipolar Absence, Generalized, Partial Prolongs Recovery Time of Na+ Channels Inhibits GABA-transaminase |
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Lamotrigine |
Anticonvulsant/Bipolar All three seizure types Blocks Na+ Channels Combination Skin Rash |
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Morphine |
Opioid Receptor Agonist Basic Structure |
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Codeine |
Opioid Receptor Agonist Not as potent Anti-tussive |
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Hydromorphone |
Opioid Receptor Agonist More potent |
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Heroin |
Opioid Receptor Agonist |
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Hydrocodone |
Opioid Receptor Agonist |
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Oxycodone |
Opioid Receptor agonist Combined with tylenol to form percocet |
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Oxymorphone |
Opioid Receptor agonist |
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Pantopium |
Opioid Receptor agonist |
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Merperidine |
Opioid Receptor agonist Less constipation |
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Fentanyl |
Opioid Receptor agonist Very potent Used in combination with other drugs |
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Diphenoxylate |
"Opioid"
Used to treat diarrhea |
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Loperamide |
"Opioid" Used to treat diarrhea |
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Methadone |
Opioid Similar to morphine, higher efficacy and extended duration of action |
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Propoxyphene |
Opioid Overdose common |
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Dextromethorphan |
Anti-tussive |
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Naloxone |
Opioid antagonist Reverses opioid effects |
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Naltrexone |
Opioid antagonist More potent than naloxone |
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Buprenorphine |
Opioid partial agonist Used as maintenance drug with naloxone |
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Cocaine |
Local Anesthetic Ester Vasoconstriction Pupil dilation Sensitization to all catecholamine effects |
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Ethyl aminobenzoate (Benzocaine) |
Local Anesthetic Ester Topical |
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Procaine |
Local Anesthetic Ester Infiltration |
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Tetracaine |
Local Anesthetic Ester Toxicity greater Spinal Anesthesia |
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Lidocaine |
Local Anesthetic Amide Potent, versatile, widely used |
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Mepivacaine |
Local Anesthetic Amide Longer acting Infiltration and spinal |
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Dibucaine |
Local Anesthetic Amide Long acting, toxic Topical |
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Bupivacaine |
Local Anesthetic Amide Longer acting |
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Phenytoin |
Anticonvulsant Hydantoin Partial and Generalized |
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Mephenytoin |
Anticonvulsant Hydantoin Partial and generalized Toxic, hepatitis, skin falls off |
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Ethotoin |
Anticonvulsant Hydantoin Partial and generalized Less toxic, less efficacious Sedation |
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Phenobarbital |
Anticonvulsant Barbiturate Partial and generalized Widely used Sedative effect, hyperactivity in children, confusion in elderly Liver interactions |
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Mephobarbital |
Anticonvulsant Barbiturate Generalized and partial Seizures Toxicity and uses same as phenobarbital |
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Primidone |
Anticonvulsant Deoxybarbiturate Generalized and partial Sedation, dizziness, nausea, vomiting Combine with other drugs |
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Carbamazepine |
Anticonvulsant/Bipolar Iminostilbene Partial and Generalized Similar to phenytoin Reducing Na+ channel function Ataxia, vertigo, blurred vision, nausea, bone marrow depression |
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Oxcarbazepine |
Anticonvulsant Partial Seizures Dizziness, nausea, vomiting |
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Eslicarbazepine acetate |
Anticonvulsant Partial Seizures Recovery of Na+ channels |
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Gabapentin |
Anticonvulsant Gaba Agonist Combination |
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Felbamate |
Anticonvulsant Partial and generalized Quickly redrawn Many risks |
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Topiramate |
Anticonvulsant Partial and Generalized Blocks Na+ Channels |
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Tiagabine |
Anticonvulsant Partial GABA uptake blocker |
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Zonisamide |
Anticonvulsant Partial and generalized |
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Ethosuximide |
Anticonvulsant Absence Effect, least toxic Inhibiting Ca2+ currents in thalamic neurons |
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Clonazepam |
Anticonvulsant Absence Not used much |
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Diazepam |
Anticonvulsant |