251 Lecture Quiz 8

Front 1

Interferons

Back 1

Interfere with viral multiplication

Front 2

Transferrins

Back 2

Make iron hard to get to slow bacterial growth

Front 3

Infra-a and B do what

Back 3

Destroy mRNA in neighboring cells to slow viruses down

Front 4

Innate immunity functions

Back 4

Prevent infection, stop infection at breach site, slow it down until adaptive response can happen

Front 5

Humoral immunity

Back 5

Extracellular, B cells - - > plasma cells

Mediated by antibodies

Front 6

Cellular immunity

Back 6

Intracellular, CD8 - - > CTL

Mediated by T cells

Front 7

Antigens

Back 7

Proteins that evoke highly specific immune response

Front 8

Epitope

Back 8

Surface features targeted by host

Front 9

Cytokines

Back 9

Chemical messengers of immune system

Front 10

Interleukins

Back 10

Communicate between leukocytes

Front 11

Chemokines

Back 11

Induce migration of leukocytes to areas of infection

Front 12

Clonal selection

Back 12

It's when an immune cell that can handle the infection is identified and told to replicate like mad

Front 13

MHC antigens

Back 13

MHC-1 function to tell the immune system what is "self"

Front 14

MHC-2

Back 14

Tell the body what the infection or infected cell looks like

Front 15

B cells

Back 15

Can recognize whole antigens, and break them into readable fragments

Front 16

T cells

Back 16

Only recognize fragments of antigens presented to them

Front 17

CD4 cells

Back 17

Tell us which immune response to activate and also activate clonal selection

Front 18

Antigen presenting cells

Back 18

Dendritic cells, macrophages, b cells

Front 19

Dendritic cells

Back 19

In Lymph nodes, spleen, skin, determine if vaccines work

Front 20

How to activate macrophages

Back 20

Make them work, or cytokines will tell them to

Front 21

B cells are a part of what immunity

Back 21

Humoral, they are filters that bind to it's antibody and then present it on MHC-2

Front 22

CD4 cells release what

Back 22

IL2 to allow division and differentiation

Front 23

TH1

Back 23

Cellular, IL2, drive the response, produce cytokines

Front 24

TH2

Back 24

Humeral, IL4, make cytokines associated with b cell activation, allergies or parasites

Front 25

CD8 make

Back 25

CTL and CD4 which requires IL2

Front 26

CD8 killing

Back 26

CTL attached to target cell, either releases host cell or releases perforin and granzymes

Front 27

B cell proliferation

Back 27

Most become antibody producing plasma cells, some become memory cells for immunological memory

Front 28

Clonal deletion

Back 28

Removes b cells that are harmful to self