Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
27 Cards in this Set
- Front
- Back
elevated alpha fetoprotein in amniotic fluid
no structural herniation |
spina bifida oculta *usually seen at lower vertebral levels
|
|
meninges herniate through spinal canal defect meningocele meninges and spinal cord herniate through spinal canal defect
|
meningomyelocele
|
|
consequence of a lesion to broca's area
|
Motor aphasia with good comprehension
|
|
consequence of lesion to wernicke's area
|
sensory aphasia with poor comprehension (fluent)
|
|
consequence of lesion to arcuate fasciculus
|
conduction aphasia; poor repitition with good comprehension, fluent speech
|
|
consequence of lesion to Amygdala (bilateral)
|
Kluver-Bucy syndrome (hyperorality, hypersexuality, disinhibition)
|
|
Consequence of lesion to frontal lobe
|
personality changes and deficits in concentration, orientation, and judgement, may have reemergence of primitive reflexes
|
|
Consequence of lesion to right parietal lobe
|
spatial neglect syndrome--left sided neglect
|
|
consequence of lesion to mamillary bodies (bilateral)
|
Wernicke-Korsakoff syndrome
|
|
Consequense of lesion to the basal ganglia
|
tremor at rest, chorea, or athetosis
|
|
Consequense of lesion to cerebellar hemisphere
|
intention tremor, limb ataxia
|
|
consequence of lesion to cerebellar vermis
|
truncal ataxia, dysarthria
|
|
consequence of lesion to subthalamic nucleus
|
contralateral hemiballismus
|
|
hemisphere vs vermis lesions of cerebellum
|
hemisphere: lateral lesion affects lateral limbs
vermis: central lesion affects central body |
|
athetosis
|
slow writhing movements, esp of fingers
characteristic of basal ganglia lesion |
|
hemiballismus
|
sudden wild flailing of 1 arm
characteristic of contralateral subthalamic nucleus lesion loss of inhibition of thalamus thru globus pallidus |
|
degeneration of cerebral cortex
Dementia, aphasia, parkinsonian sx intracellular aggregated tau protein specific for frontal and temporal lobes dx? |
Pick's disease
|
|
degenerative disease of cerebral cortex
Dementia, aphasia, parkinsonian intracellular aggregated tau protein specific for frontal and temporal lobes |
Pick's disease
|
|
protein's associated with familial alzheimers
|
chromosme 1, 14, 19: APOE4 allele
Chrom 21: p-App gene |
|
autosomal dominant inheritance
chorea and dementia atrophy of caudate nucleus (loss of GABAergic neurons) |
Huntington's
|
|
autosomal dominant inheritance
chorea and dementia atrophy of caudate nucleus (loss of GABAergic neurons) |
Huntington's disease
|
|
Prarkinsons
Pathological anatomy and histology |
Lewy bodies and depigmentation of the substantia nigra pars compacta
|
|
Spinocerebellar deiseases, err wtf
|
Olivopontocerebellar atrophy; Friedreich's ataxia
|
|
Biochemical genetics of huntington's
|
Chromosome 4 expansion of CAG repeats
CAG=Caudate loses Ach and Gaba |
|
Tremor type in Parkinson's
|
resting
TRAP= Tremor (resting); Rigidity (cogwheel); Akinesia; Postural instability 'trapped in body' |
|
dx:
floppy baby w/ tongue fasciculations death at 7 months |
Wernig-Hoffmann disease
***degeneration of anterior horns *** |
|
Polio symptoms, pathology
|
LMN signs
degeneration of anterior horns poliovirus |