1.1 Introduction:
More than 200 different species of bacteria normally live on the skin
(Benbow, 2010) and an open wound provides a moist, warm and nutritious environment perfect for microbial colonisation and proliferation (Young, 2012).
When one or more microorganisms multiply in the wound, local and systemic responses occur in the host, which can lead to infection and a subsequent delay in healing (Angel et al., 2011).
Cutting (2010) mentioned that maintaining the bacteria at a level at which the host is in control is an important part of avoiding wound infection.
In 2001, Bowler et al. found that when chronic wounds are poorly perfused they are more susceptible to infection, as blood delivers oxygen, …show more content…
The use of probiotics as an alternative therapy for treatment and prevention of bacterial infections has been reported (Bomba et al., 2006).
Gorbach (2000) pointed out there is a growing interest in probiotics as a safe therapeutic agent through their ability to alleviate food allergies, enhance nonspecific and specific immune responses, suppress intestinal infections, and anticarcinogenic activity (Grajek et al., 2005).
According to Doron and Gorbach, (2006) probiotics possess many mechanisms to exert their beneficial effects; they prevent colonization, cellular adhesion, invasion by pathogenic organisms, they have antimicrobial activity, and they modulate the host immune response.
Vinegar is a sour liquid comprised mainly of acetic acid, typically 4-18% acetic acid by mass, which is prepared in households by the fermentation of many fruits, the solution is also commercially available, it is cheap and easily found in markets (Ismael, 2013).
Vinegar has been shown to be effective in the prevention and control of microbial contamination in intra-canal treatment of apical periodontitis in teeth (Estrela et al.,