This process results in hyperkalemia, hyperphosphatemia, hypocalcemia and hyperuricemia.
TLS can lead to a variety of renal, neurological and musculoskeletal manifestations and therefore can be life-threatening.
A. Philip Randolph was born on April 15, 1889 in Crescent City, Florida. His mother and father were Elizabeth and James Randolph. He had one brother named James Randolph. When he was young, he went to the Cookman Institute of Education; it was an all black- male school. He then went to the City College of New York.…
With the current available treatments and medication as well as the early diagnosis, SLE is considered a chronic disease with relatively lower mortality rates[90]. SLE symptoms usually present during the first years of obtaining the disease, but can progress quite slowly and be mistaken for other diseases[24][29]. The severity of SLE ranges from benign and can rapid progress to possibly fatal [25]. Fortunately, many patients can manage SLE with medication and live a normal life span [62]. There are several valid systems that measure SLE disease activity and symptom severity, such as the Systemic Lupus Activity Measure (SLAM), SLEDAI, Lupus Activity Index (LAI), European Consensus Lupus Activity Measurement (ECLAM), and British Isles Lupus Activity Group (BILAG) Index [25].…
Duchenne Muscular Dystrophy Do you know what duchenne muscular dystrophy is? It obviously has something to do with your muscles it causes you to have muscle weakness which can lead you to have loss of mobility. This disease is most effective for males. Duchenne muscular dystrophy is a mutation, flaw or gene.…
My favorite subject that we spoke about in class is when we learned about Osgood-Schlatter Disease because I have this disease. We learned in class that Osgood-Schlatter Disease is when muscles become too tight because of rapid growth in the epiphyseal plate. The epiphyseal plate is a growth plate that is only in children and adolescence. The epiphyseal plate is at the superior end of the tibia by the tibial tuberosity. My doctor told me that this disease effects when I am physically active, which is difficult because I regularly play tennis, an anaerobic activity.…
Our research centered around acute myelogenous leukemia (AML) and the Warburg Effect. The Warburg Effect describes the tendency of proliferating cells and cancer cells to convert glucose into lactate despite adequate levels of oxygen. As it has been previously revealed that leukemia cells produce lactate even in the presence of oxygen, we hypothesized that AML cells specifically are dependent on aerobic glycolysis and that treatment with dichloroacetate will stimulate apoptosis. We further hypothesized that apoptosis would be the result of the cells switching from aerobic glycolysis to oxidative phosphorylation, resulting in an increase in mitochondrial activity and reactive oxygen species and a decrease in survival proteins Bcl-2 and survivin.…
Carpal Tunnel Syndrome(CTS) happens when your median nerve, which runs from your forearm into the palm of your hand, becomes pressed or squeezed at your wrist. Your median nerve provides feeling to your palm side of your thumb & to your index, middle, & part of your ring fingers. Meaning you won’t feel those fingers move or crack. It’s also not a disease which means you can’t catch it from someone else. Carpal Tunnel Syndrome is often the result of a combination of factors that reduce the available space for the median nerve within the carpal tunnel, rather than a problem with the nerve itself.…
Overview Non-Hodgkin’s lymphoma is any cancer that begins within the lymphatic system. Normally old white blood cells, called lymphocytes, die while new ones are produced. In non-Hodgkin’s lymphoma, old cells instead multiply and divide. The body starts to accumulate large numbers of these abnormal cells, and this often leads to the formation of tumors. There are various types of this condition, including diffuse large and marginal B-cell lymphomas, follicular lymphoma, chronic lymphocytic leukemia, mantle cell lymphoma, Burkitt lymphoma, hairy cell leukemia, and peripheral T-cell lymphomas.…
Cushing’s syndrome is caused from the over production of the adrenal cortisol due to hyperfunctioning of the adrenal glands. The Cushing’s syndrome based on its pathophysiology expresses itself in different types, namely: ACTH-dependent Cushing’s syndrome, Ectopic ACTH syndrome and ACTH-independent Cushing’s syndrome. The condition clinically manifests signs such as central obesity and facial rounding which is about 90% in patients. Peripheral obesity and fat accumulation is also seen in about 50% of patients. In addition, other findings include glucose intolerance, muscle weakness and gonadal dysfunction among others.…
Tesco has a responsibility to make reasonable adjustments where applicable, to provide a premises which have the facilities for a disabled person different from a person that are not disabled. Furthermore, Tesco also, supports the ‘Positive about disabled people' scheme (the Two Tricks System) which means we guarantee to interview every applicant that has a disability and meets the minimum criteria for the vacancy. Under this scheme applicants that are invited for interview, will be asked if they required any reasonable adjustment to be made for the interview.…
Viet Tran Period 4 4/4/2017 Impetigo 1. What is Impetigo mean? It’s also known as a school sores, a bacteria inflection a skin and make red sores on your face.…
First discovered by neurologist Jean-Martin Charcot in 1869, Amyotrophic Lateral Sclerosis (ALS), commonly known as Lou Gehrig’s disease, is a fatal age-related progressive neurodegenerative disease [8, 9]. It first arises within the central nervous system (CNS) and then spreads ceaselessly. ALS is characterised by the selective denervation and death of lower (LMN) and upper motor neurons (UMN). It is the most common motor neuron disease with an incidence of 1.5 to 2 per 100 000 individuals per year with an estimated prevalence of 12 000 people within the total US population [10, 11]. On average, newly diagnosed patients die within 3 to 5 years from onset after succumbing to respiratory failure due to muscle atrophy and weakness [12,13].…
Spondylolysis is defined as a structural defect that involves the breaking down of the vertebra (Hockenberry & Wilson, 2015). Symptoms of this condition include lower back and lower limb pain. In fact, spondylolysis is one of the common causes of back pain in adolescents, particularly young athletes. This injury most often occurs on children and adolescents who are involved in sports that place repeated stress on the lower back. Furthermore, in some cases spondylolysis can lead to spondylolisthesis, when the vertebra begins to shift out of place (Hockenberry & Wilson, 2015).…
It is a disease where abnormal cells in the body divide without any control and can attack other tissue. How is it spread? Cancer cells spread through the lymph system and blood system. Some familiar types of cancer include liver, breast, lung, ovarian, bladder, prostate, and…
Usher Syndrome Usher syndrome is a condition that causes hearing loss and vision loss. There are three types of Usher syndrome: Type 1. Children with this type have severe hearing loss and balance problems at birth. Vision problems usually develop before age 10, and vision loss quickly progress to total blindness. Type 2.…
Asbestos related disease is responsible for 30 deaths per day, or 10,000 deaths per year. Asbestos diseases kill thousands more people than other types of cancers that get much more attention from the government and pharmaceutical companies. In addition, all asbestos exposed individuals should discuss smoking cessation efforts with their physicians as smoking can compound the effects of asbestos, increasing the risk of developing an asbestos related disease . Smokers have a significantly higher risk of contracting an asbestos related disease than non-smokers. As many as 1 in 100 men over the age of 40 in this country will develop a malignant asbestos related disease, as well as an increasing number of women.…