The Metabolism Hypothesis

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Replication, first, came about because RNA was formed. This occurred because organic molecules on Earth were able to form ribonucleotides from the assistance of a clay catalyst. Eventually, these ribonucleotides formed RNA, which, through time, began to fold and replicate itself. As replication got faster, RNA's started to attract amino acids and hold them together. Bonds started forming, and proteins were able to be produced. As more years passed, a lipid membrane enclosed the structure to protect the RNA and proteins, and DNA took RNA's place due to DNA's superior stability. Before metabolism was established, RNA was created and began replicating itself on early Earth in order to create life. RNA, in the beginning, assembled from organic …show more content…
Metabolism's mechanism of a reverse Kreb's Cycle in order to create organic molecules has been shown to be too slow to create life in a billion year time frame ("Part lll--Team 2: Intimate Debate Handout," 2). This revelation knocks down the idea of metabolism-first because the process is not fast enough to produce life in the time estimated by experts of when life first originated. The reverse Kreb's Cycle is the theory that Hydrogen Sulfide and Iron Sulfide were released from hydrothermal vents in the deep sea. When Hydrogen Sulfide and Iron Sulfide combined, they created Triolite, which acted as the catalyst since it could use its electron and combine with Carbon. That combination would create organic molecules, which are made from this process along with the first membrane. However, this complicated process would have taken too much time to create life. Additionally, the temperature at the hydrothermal vents were not suitable for Triolite to give its electron away to carbon, so it is unlikely that Iron Sulfide could have been used as a catalyst ("Part lll--Team 2: Intimate Debate Handout," 2). Without a catalyst, the reactions would have occurred too slowly; thus, life would not be formed in a quick enough manner. Unsuitable conditions and time consuming processes make metabolism-first an unlikely …show more content…
The organic molecules needed to make RNA were already established on Earth as proven by the existence of organic molecules on meteors and comets. RNA, also could have served as a catalyst because RNA still does so today; plus, Thomas Cech proved that RNA can act as a catalyst, which won him a Nobel Prize. Not to mention, metabolism-first has major mechanism problems because the process is too slow to even create life in the time frame of a billion years. Also, the temperature at the hydrothermal vents, in the deep sea, was not suitable for Triolite to act as a catalyst, and without a proper catalyst, the reaction would occur too slowly. Sure, replication-first has its own problems, but research is still being done to find RNA that can replicate identically. Plus, ancestral RNA could have figured out how to fold in such a way that it became a catalyst that could copy itself accurately. RNA is still a fundamental replicating tool in our cells that is used to create proteins to this day. Starting from organic molecules, RNA formed in order to create the life that roams the Earth

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