Diffuse Optical Tomography Essay

Diffuse Optical Tomography is non invasive, non ionizing functional imaging modality used for detection of brain tumor and breast cancer. A forward model design depicts the placement of laser source and photo-detector around the tissue boundary. The light propagation on the phantom takes place in Near-Infra-Red wavelength. The incident light on the tissue boundary was absorbed and scattered. The scattered rays are detected by the photo-detector and scattered voltage of the tissue was measured. The scattered voltages vary for normal and tumor cell in the range of (0.1-4.3) volts and (4.3-5) volts respectively. This system of forward model acts as a screening test for the patients suffering from brain tumor. The parameters measured from forward …show more content…
The screening of the tumor is significant to enhance the patient life. The existing screening methods by image modeling are Computer Aided Tomography, Positron Emission Tomography, Magnetic Resonance Imaging and Ultra-sound scanning. The above mentioned functional imaging modalities are non invasive but operates with ionizing radiations to reconstruct the phantom image. Proposed system is Diffuse Optical Tomography (DOT) [1] is non-ionizing since it works in Near-Infra-Red wavelength (700-1100) nm. The system is portable [2], low cost, real time imaging with increased clinical applications. Forward modeling [3] includes the concept of using a grid of light sources and light detectors which is positioned on the organ of the subject which is under examination. Often this is done using fiber optics where one end of the fiber is secured into the organ of the subject, and the other end of the fiber is connected to the imaging instrument. The arrangement of the fiber on the organ determines the depth-sensitivity of the measurements to underlying changes, which is a function of the distance between the source and