Animal testing started in the 17th century.
Already in 1990, ZEBET had an international committee convened to develop a scientific concept for the experimental validation of toxicological testing methods. Scientists at ZEBET are involved in the development of OECD Test Guidelines and Guidance Documents which has led to an …show more content…
In Europe of the animals tested, 79% are mammals, with rodent, and here mainly mice and rats, making up for 75% of total animals; another 2.6% are rabbits. Only for toxicology and safety evaluation, about 970,000 animals were used in 2005, with an 8% total. The largest share of animals required for toxicology and safety testing of 42% was used for acute and subacute toxicity testing. A second large fraction of 17.7% was used for testing carcinogenicity, mutagenicity, and toxicity to reproduction.in 2003, the EU adopted the Registration, Evaluation, and Authorization of Chemicals existing chemicals within a period of 15 years. The number of Additional animals required for toxicology and safety testing over this period has been estimated at 9 million. In 2005, testing for sub chronic and chronic toxicity and CMR together accounted for roughly 30% of animals used for toxicology and safety