MOSCOW, July 2 - RIA Novosti. US bioengineers were able to successfully suppress the growth of skin cancer cells using microspheres of gold nanoparticles and spherical molecules of RNA, and published their findings in an article in the journal Proceedings of the National Academy of Sciences.
"Now we can start a fight with a host of diseases. Thanks to the project "Human Genome" and all work in this area over the past two decades, we have a long list of possible "targets" in our genome. And to get into them, we can use one tool - the scope of the nucleic acid, "- said the head of a group of scientists Chad Mirkin (Chad Mirkin) from Northwestern University in Evanston (USA). …show more content…
As the researchers note, most of the genome of these cells, "edited" with artificial retrovirus, delete, or insert the desired DNA fragments. In recent years, scientists have successfully tested viruses, volunteers cure HIV and leukemia. Nevertheless, biologists fear that these drugs can cause side effects and irreversible penetrate heritable genetic material.
The authors were able to avoid this problem by developing a new system for gene delivery into cells that could penetrate the barriers of the immune system and physical barriers. The basis for a new therapy were the gold nanoparticles surrounded by a shell of a plurality of spherical molecules of RNA.
According bioengineers, spherical particle structure allows it to pass unobstructed through the immune barrier on the surface of the skin and pass through the pores in the cell walls. When nanosphere penetrates the cell, it opens and the cell is flagged plurality of short fragments of RNA or DNA, neutralizing work damaged genes.
And the cure for