Abstract
Although initially considered a rarity, primary aldosteronism now is considered one of the most common causes of secondary hypertension. Litynski reported the first cases, but Conn was the first to well characterize the disorder, in 1956. In this report, it is discussed the diagnosis and management of primary aldosteronism during pregnancy. Aldosterone and renin are physiologically increased during pregnancy and confirmation tests are not recommended, the diagnosis of primary aldosteronism during pregnancy relies on a repeatedly suppressed plasma renin level. Mineralocorticoid receptor antagonists (MRAs) are the most effective drugs to treat hypertension and hypokalemia in primary aldosteronism. However, spironolactone might lead
Although initially considered a rarity, primary aldosteronism now is considered one of the most common causes of secondary hypertension. Litynski reported the first cases, but Conn was the first to well characterize the disorder, in 1956. In this report, it is discussed the diagnosis and management of primary aldosteronism during pregnancy. Aldosterone and renin are physiologically increased during pregnancy and confirmation tests are not recommended, the diagnosis of primary aldosteronism during pregnancy relies on a repeatedly suppressed plasma renin level. Mineralocorticoid receptor antagonists (MRAs) are the most effective drugs to treat hypertension and hypokalemia in primary aldosteronism. However, spironolactone might lead