PLATELET RICH FIBRIN USED IN THE REGENERATION OF INTRAOSSEOUS DEFECT IN AGGRESSIVE PERIODONTITIS PATIENT – A CASE REPORT
ABSTRACT (Words: 127)
Background: Platelet rich fibrin (PRF) is a fibrin matrix made of platelets, cytokines and growth factors. It releases growth factors essential for regeneration for healing.
Case Report: PRF was obtained by a simple process from a generalized aggressive patient. PRF obtained was placed in the intraosseous defect during open flap debridement. This case presents regeneration of intraosseous defect by adjunctive use of along with PRF open flap debridement. A follow up of one year showed reduction in clinical probing depth, gain in clinical attachment and increase in radio density on post operative radiograph.
Conclusions: The healing of periodontal defect observed as there was gain of clinical attachment. The potential of PRF in periodontal surgery for regeneration of intraosseous defects in aggressive periodontitis patient should be further studied.
Key words: platelet rich fibrin, intraosseous, aggressive periodontitis INTRODUCTION
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The periodontal flap was elevated with respect to 31 and 41 region. A two walled defect was found in respect to 31 on surgical exploration. The defect was completely debrided (Figure 3). Patient blood was derived and immediately transferred into test tube. The test tube was placed into centrifugation machine and centrifuged at the 3000 revolutions per minute (rpm) for 10 min. The test tube showed supernatant plasma, platelet concentrate and red blood cells at the bottom. The platelet rich fibrin (PRF) obtained was then placed in the defect (Figure 4). The healing was uneventful. A follow up of 6 months showed reduction in clinical probing depth and increase in radio density on the post operative radiograph suggestive of regeneration (Figure 5 and Figure