Cancer is known as a group of diseases involving abnormal cell growth that has the potential to spread or invade to other parts of the body.
“Cancer can start almost anywhere in the human body, which is made up of trillions of cells. Normally, human cells grow and divide to form new cells as the body needs them. When cells grow old or become damaged, they die, and new …show more content…
“Regenerative medicine holds promise for the treatment of degenerative and genetic diseases” (Marini, 2012, pg 2522). They serve as an internal repair system and divide without limit to replenish other cells. They are different than normal cells in two ways. Firstly, they are unspecialized cells that care able to renew themselves though cell division after long periods of inactivity. Secondly, in some conditions they can be induced to become tissue or organ specific cells with certain special functions. (National Institutes of Health, 2015). “When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell” (National Institutes of Health, 2015).
There are two types of stem cells. Embryonic stem cells and Somatic stem cells. Embryonic stem cells are defined by the National Institutes of Health as, “Primitive (undifferentiated) cells derived from a 5-day preimplantation embryo that are capable of dividing without differentiating for a prolonged period in culture, and are known to develop into cells and tissues of the three primary germ layers” (2015). Somatic stem cells are defined …show more content…
It remains to be established whether chimeric antigen receptor T cells have clinical activity in AML” (Grupp, 2013, pg 1509). An experiment has been done with another type of modified T cell. This one showed promise for CLL and scientists are working on testing it for ALL as well. It shows lots of promise for the future.
Dawson (2012) found that “In primary human MLL-translocated leukemia cells, BET [bromodomain and extraterminal proteins] inhibition dramatically reduced the clonogenic capacity of the leukemia stem-cell compartment, suggesting that disease eradication may be possible” (pg 655). Bromodomain and extraterminal proteins are a family of proteins that influence gene expression, cell-cycle regulation, and development. A melanoma is a cancer of the melanocytes. These are the cells that make myelin (this pigment gives skin its color). Most melanomas form on the skin, but they can also be found in other pigmented tissues, such as the eye. It is rare, only 2% of all skin cancers are melanoma. It does, however, cause the most deaths from skin cancer. (National Cancer Institute,