Layers Of Epidermis Research Paper

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Layers of Epidermis:
1. Stratum basale: The stratum basale or stratum germinativum is a continuous layer which gives rise to keratinocytes. It is usually described as one cell thick .this is the base or bottom made of living cuboidal keratinocytes that undergo cell division (mitosis ) they also have melanocytes that make melanin( dark pigment ).
2. Stratum Spinosum: the stratum spinosum or prickle cell layer is so called because the cells are given a spiny appearance by the numerous desmosomes or attachment plaques at their surfaces. These are belived to be tonofibrils that maintained the tonous of epidermis.In the upper layer of stratum spinosum membrane coating granules, known as odland bodies are seen.These are ovoid bodies about 100-500nm long.their function is unknown though they appear to contain mucopolysaccharides.
3. Stratum Granulosum: The stratum spinosum
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Stratum Corneum: This is the outermost layer of the epidermis, consisting of dead cells (corneocytes). This layer is composed of 15-20 layers of flattened cells with no nuclei and cell organelles. Their cytoplasm shows birefringent filamentous scleroprotein keratin. The purpose of the stratum corneum is to form a barrier to protect underlying tissue from infection, dehydration, chemicals and mechanical stress. Desquamation, the process of cell shedding from the surface of the stratum corneum, balances proliferating keratinocytes that form in the stratum basale. These cells migrate through the epidermis towards the surface in a journey that takes approximately fourteen days. Cells of the stratum corneum contain a dense network of keratin, a protein that helps keep the skin hydrated by preventing water evaporation. These cells can also absorb water, further aiding in hydration. In addition, this layer is responsible for the "spring back" or stretchy properties of skin. A weak glutenous protein bond pulls the skin back to its natural shape. The thickness of the stratum corneum varies throughout the

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