1. What is the difference between calcium carbonate and hydroxyapatite?
Calcium carbonate is more soluble than hydroxyapatite.
2. What are the pitfalls of using CHA in bone graft procedures?
CHA is fragile an brittle and it should only be used temporarily
3. What is CHACC and what potentially makes it better than CHA?
CHACC is Coralline Hydroxyapatite/calcium carbonate. CHACC is better than CHA because it can keep a porous structure as well s biocompatibility making it a even better player for bone grafts. There are improved biodegradation proprieties that can be suitable for bone remodeling to support natural bone healing process.
4. What is being shown in figure 1?
Figure 1 shows the surface structure of CHACC using a Scanning electron micrographs at different levels of …show more content…
Summarize the results of figure 4.
Figure 4a shows that CHACC had a slower progressive growth rate and number of cells than the control, but CHACC resulted with the higher number of cells. Figure4b shows that even though there was a larger amount of DNA that could be extracted from the control there were still almost even amounts from CHACC. Figure4c shows that CHACC contained high amounts of alkaline phosphatase much greater than the control. Figure4d shows similar results to figure 4c. The amounts of alkaline phosphatase per DNA were much greater than the control.
5b. What does alkaline phosphatase (AP) measure?
Alkaline phosphatase measures the amount of alkaline phosphatase enzymes in the blood stream.
6. Summarize the findings in figure 5. Do you agree with the findings? Why or why not?
Micrographs of osteogenic assessment of hMSCs on CHACC, by electron microscopy in vitro (A–D) and light microscopy in vivo
(E), (F). (A), (C) hMSCs on CHACC, 16 days in control culture medium. (B), (D) hMSCs on CHACC, 16 days in osteogenic medium.
Notice the rougher and more mature collagen fibres in (D) in comparison with (C). (E) CHACC + risedronate, implanted alone
Calcium carbonate is more soluble than hydroxyapatite.
2. What are the pitfalls of using CHA in bone graft procedures?
CHA is fragile an brittle and it should only be used temporarily
3. What is CHACC and what potentially makes it better than CHA?
CHACC is Coralline Hydroxyapatite/calcium carbonate. CHACC is better than CHA because it can keep a porous structure as well s biocompatibility making it a even better player for bone grafts. There are improved biodegradation proprieties that can be suitable for bone remodeling to support natural bone healing process.
4. What is being shown in figure 1?
Figure 1 shows the surface structure of CHACC using a Scanning electron micrographs at different levels of …show more content…
Summarize the results of figure 4.
Figure 4a shows that CHACC had a slower progressive growth rate and number of cells than the control, but CHACC resulted with the higher number of cells. Figure4b shows that even though there was a larger amount of DNA that could be extracted from the control there were still almost even amounts from CHACC. Figure4c shows that CHACC contained high amounts of alkaline phosphatase much greater than the control. Figure4d shows similar results to figure 4c. The amounts of alkaline phosphatase per DNA were much greater than the control.
5b. What does alkaline phosphatase (AP) measure?
Alkaline phosphatase measures the amount of alkaline phosphatase enzymes in the blood stream.
6. Summarize the findings in figure 5. Do you agree with the findings? Why or why not?
Micrographs of osteogenic assessment of hMSCs on CHACC, by electron microscopy in vitro (A–D) and light microscopy in vivo
(E), (F). (A), (C) hMSCs on CHACC, 16 days in control culture medium. (B), (D) hMSCs on CHACC, 16 days in osteogenic medium.
Notice the rougher and more mature collagen fibres in (D) in comparison with (C). (E) CHACC + risedronate, implanted alone