Context
Bone scans are used to detect abnormalities in the bone due to its uptake in osteoblasts (Ka kit, W. and Morand, P. 2013). Patients who have bone scans are instructed not to adjust their diet prior to having a bone scan. Patients who are already booked for bone scans can be given supplements prior to their scan date and then scanned. Normal bone scans as well as scans of patients who had been on bone supplements which are of a similar body habitus will be given to radiologists who won’t know which scans are of patients who have been on bone supplements and which are of normal patients. The radiologist will rate the quality of the uptake as well as draw ROIs (regions of interest) over areas to compare differences in uptake. If there is a clear distinction between patients that had supplements and those that did not then a correlation between bone supplements and the quality of a bone scan would have been established. If there is an increase in uptake then patients could be advised to take bone supplements if it’s readily available or even increase the amounts of vitamins in their diet prior to having a bone scan. This will then allow radiographers to obtain clearer images of bones in a bone scan and therefore make it easier for radiologists to report on bone scans. Hyperthyroid as well as hypothyroid patients will be excluded from the group due to the role that the thyroid plays with calcium regulation in the body. Therefore this study aims to investigate the effect of bone supplements on bone scans in terms of image quality and/or radionuclide uptake in bone in order to raise awareness of any effects of bone supplements on bone scans. Literature Review Introduction The adsorption of Tc 99m-MDP into bone showing how hydroxyapatite adsorption can be affected by environmental factors such as the pH, which affects the adsorption as well as the crystalline structure of hydroxyapatite being able to affect the adsorption of 99mTc –MDP has been observed in the presence of phosphates, calcium ions and other cations. …show more content…
(Okamoto 1995). Kanishi (1993), had observed using a variety of things which included hydroxyapatite powder that Methylene Diphosphonate accumulation is taken up into the bone by chemical adsorption onto the surface of hydroxyapatite in bone as well as incorporation into the crystalline structure of hydroxyapatite. Furthermore he also observed that, there isn’t a correlation between the 99mTc-MDP accumulation and the number of osteoblast like cell numbers. Discussion Calcium aids vitamin D in bone repletion in patients with a vitamin D defieciency by normalising bone mineralization, turnover as well as skeletal integrity and this supplementation of vitamin D combined with calcium showed higher bone mineral density in the spine which increased by 9.5%% after fourteen months of treatment (Lafage-Proust et al 2013).The research also discusses the method of uptake of Methylene Diphosphonate (MDP) into bone as well as a background explanation of the composition of bone (Ka kit and Morand 2013). There are supplements available for the public which when combined with calcium increases bone health and this could be used in the research to compare the differences in the bone scan before supplementation use as well as afterwards (Cleveland Clinic 2015). Calcium is important in the body and serves many functions some of which include roles in helping to send messages in your nervous system, blood clotting, muscle contraction …show more content…
Patients that will be excluded will be patients that
- have thyroid problems
- are unfit patients
- are on a stretcher or wheel chair in order to minimise their discomfort and reduce the time they spend in the department filling out a consent form as well as having to have to take bone supplements.
- Patients excluded will also be those patients in which the injection gets tissued (the entire injection isn’t intravenous some are intramuscular).
- Hyperthyroid as well as hypothyroid patients will be excluded from the group due to the role that the thyroid plays with calcium regulation in the body.
Data to be collected: the data that will be collected will be the bone scan images as well as the amount of radioactivity injected and the time the patients are injected as well as the time they are scanned. The data collected will be primary data which will be collected personally while working in the
Bone scans are used to detect abnormalities in the bone due to its uptake in osteoblasts (Ka kit, W. and Morand, P. 2013). Patients who have bone scans are instructed not to adjust their diet prior to having a bone scan. Patients who are already booked for bone scans can be given supplements prior to their scan date and then scanned. Normal bone scans as well as scans of patients who had been on bone supplements which are of a similar body habitus will be given to radiologists who won’t know which scans are of patients who have been on bone supplements and which are of normal patients. The radiologist will rate the quality of the uptake as well as draw ROIs (regions of interest) over areas to compare differences in uptake. If there is a clear distinction between patients that had supplements and those that did not then a correlation between bone supplements and the quality of a bone scan would have been established. If there is an increase in uptake then patients could be advised to take bone supplements if it’s readily available or even increase the amounts of vitamins in their diet prior to having a bone scan. This will then allow radiographers to obtain clearer images of bones in a bone scan and therefore make it easier for radiologists to report on bone scans. Hyperthyroid as well as hypothyroid patients will be excluded from the group due to the role that the thyroid plays with calcium regulation in the body. Therefore this study aims to investigate the effect of bone supplements on bone scans in terms of image quality and/or radionuclide uptake in bone in order to raise awareness of any effects of bone supplements on bone scans. Literature Review Introduction The adsorption of Tc 99m-MDP into bone showing how hydroxyapatite adsorption can be affected by environmental factors such as the pH, which affects the adsorption as well as the crystalline structure of hydroxyapatite being able to affect the adsorption of 99mTc –MDP has been observed in the presence of phosphates, calcium ions and other cations. …show more content…
(Okamoto 1995). Kanishi (1993), had observed using a variety of things which included hydroxyapatite powder that Methylene Diphosphonate accumulation is taken up into the bone by chemical adsorption onto the surface of hydroxyapatite in bone as well as incorporation into the crystalline structure of hydroxyapatite. Furthermore he also observed that, there isn’t a correlation between the 99mTc-MDP accumulation and the number of osteoblast like cell numbers. Discussion Calcium aids vitamin D in bone repletion in patients with a vitamin D defieciency by normalising bone mineralization, turnover as well as skeletal integrity and this supplementation of vitamin D combined with calcium showed higher bone mineral density in the spine which increased by 9.5%% after fourteen months of treatment (Lafage-Proust et al 2013).The research also discusses the method of uptake of Methylene Diphosphonate (MDP) into bone as well as a background explanation of the composition of bone (Ka kit and Morand 2013). There are supplements available for the public which when combined with calcium increases bone health and this could be used in the research to compare the differences in the bone scan before supplementation use as well as afterwards (Cleveland Clinic 2015). Calcium is important in the body and serves many functions some of which include roles in helping to send messages in your nervous system, blood clotting, muscle contraction …show more content…
Patients that will be excluded will be patients that
- have thyroid problems
- are unfit patients
- are on a stretcher or wheel chair in order to minimise their discomfort and reduce the time they spend in the department filling out a consent form as well as having to have to take bone supplements.
- Patients excluded will also be those patients in which the injection gets tissued (the entire injection isn’t intravenous some are intramuscular).
- Hyperthyroid as well as hypothyroid patients will be excluded from the group due to the role that the thyroid plays with calcium regulation in the body.
Data to be collected: the data that will be collected will be the bone scan images as well as the amount of radioactivity injected and the time the patients are injected as well as the time they are scanned. The data collected will be primary data which will be collected personally while working in the