DESCRIPTION
Attention Deficit/Hyperactivity Disorder (ADHD) is a disorder that affects the brain, causing structural and functional abnormalities1 …show more content…
However, as Rastmanesh’s review article states, “DA-deficit theory of ADHD is insufficient to cover critical aspects of ADHD pathology and medication”.9 Further research has also indicated that other neurotransmitter systems such as the adrenergic, serotoninergic, nicotinergic and cholinergic systems may be involved.10
The accepted disease mechanism of ADHD among most researchers is low levels of dopamine.11 Dopamine pathways are directly responsible for cognitive control of behaviour, motivation, reward perception and motor function, collectively called “executive functions”.12 Dopamine is a neurotransmitter that sends signals between nerve cells, a deficiency results in impaired signals and thus impaired cognitive control, specifically the executive function, causing the symptoms of …show more content…
There are several cases under which stimulants are contraindicated. Due to the nature of stimulants and possible side effects, patients with any of the following conditions should not use stimulants as a treatment: history of alcoholism/substance abuse, anxiety, arteriosclerosis, cardiac disease, glaucoma, allergies (to methylphenidate, amphetamine or fructose/glucose/galactose/sucrose intolerance or deficiencies), hyperthyroidism or Tourette’s syndrome.16
The prognosis for ADHD is commonly very positive. Although no cure exists for ADHD, those affected can take advantage of the wide range of treatments including: medication, behavioural therapy and creating a structured school/home life. Those affected by ADHD often learn how to best live with their disease and accommodate as they mature.16
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