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Small Gram negative rods with a single polar flagellum
Aerobic
Does not ferment lactose
Cultures blue green
Grape like odor
Pseudomonas aeruginosa
Commonly found in water and soil.
Intestinal resident of 10% of healthy people
What are the virulence factors of Pseudomonas aeruginosa?
*Pili that aid in attachment to host cells
*Phagocytosis-resistant slime layer that aids in formation of a biofilm
*Enzymes that degrade host tissues
*Exotoxins
*LPS layer - endotoxins
What type of patients get the most severe infections with P. aeruginosa
Burn victims
Neoplastic disease
Cystic Fibrosis
What serious ailments can occur after being infected with P. aeruginosa?
Endocarditis
bronchopneumonia
meningitis
What are some ailments that an otherwise healthy adult might encounter after being infected with P. aeruginosa?
Skin rash
UTI
outer ear infection
Small gram negative coccobacillus typically found singly or in pairs - nonmotile
B. pertussis
Distinguished by biochemical tests - oxidase positive. Urease, nitrate reductase and citrate negative.
DNA test to detect polymerase chain reaction used to identify
What are the virulence factors of B. pertussis?
Fimbriaelike adhesion molecules - allows it to recognize and bind to ciliated respiratory epithelial cells
Exotoxins that destroy host cells
What are the two stages of whooping cough?
Catarrhal stage - mucus builds in airways, nasal drainage, congestion, sneezing and occasional coughing.
Paroxysmal stage - persistent coughing, followed by deep inhalations. Characteristic whoop sound
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