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What are the obstacles for studying the cells of the nervous system?
1) Size
2) Nervous tissue/cells are like jello, so we need to harden them to make sections for slides
3) Cells are transparent and need to be stained to be visualized
What was the first identified neuron, why, and where do we find them?
Pukinje cells because they're huge cerebellum neurons
Describe the first identified neuron
Purkinje Cells are some of the largest neurons with a long axon and a giant dendritic tree. I'm talking massive **** here.
What are the 2 stains used to identify nervous system cells? How do they differ in their staining ability?
Golgi staining stains all of the neuron, but unfortunately only like 15-20% of cell density
What is the benefit of golgi staining?
It shows the entire dendritic tree and orientation of the neuron relative to others
Who published a paper on silver nitrate staining and believed in the reticular theory of the brain? What is the reticular theory?
Camillo Golgi. Reticular theory means all neurons are physically connected in a net as a giant continuous system
Who one-upped Golgi's stainng procedure then killed his stupid little reticular thoery? What was proposed instead? How was this theory flawed too?
Cajal improved golgi's staining and described nerves as independent elements thus founding the neuron doctrine. He was close, but we described neurons are communicating via contact not continuity.
This "Sir" came along after Cajal and Golgi shared their nobel prize in 1906 and finally got it right by proposing the concept of ______ as a place of communication for neurons. Who am I and what did I propose?
Sir Charles Sherrington proposed the synapse and walked away with a nobel in medicine in 1932
What is the function of the sensory neuron and define nerve.
Sensory neurons bring information to the CNS and nerves include blood vessels + bundles of neural axons
How can we differentiate between an axon and a dendrite?
Axons can branch out at any point whereas dendrites can only branch at their ends
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