Due the extensive size of the genome, 6.3 million base pairs, P. aeruginosa is capable of adapting to a wide variety of environments …show more content…
aeruginosa is a serious threat to immune-compromised patients. It accounts for 35-40% of urinary tract infections in the hospital (Black 2012). In respiratory infections, such as pneumonia it causes hemorrhages and damages the respiratory airways that can be fatal as it causes an inflammatory response (Descamps et al. 2012). This pathogen is known to be the leading cause of respiratory infection in the world (Descamps et al. 2012), which can be ventilator-associated or hospital-acquired pneumonia. In chronic pneumonia, such as in cystic fibrosis, P. aeruginosa is the most frequent cause of mortality (Descamps et al. 2012). The inability to clear trapped bacteria in the mucous promotes microbial colonization and damages the lungs causing poor pulmonary function.
Pseudomonas aeruginosa is also known to be a common causative agent of wound infections. These wound infections are more common in people with weaker immune systems, such as those with diabetes mellitus, as it causes wounds to heal at a slower rate which makes them prone to infections. P. aeruginosa wound infections occur most often in the hospital from surgical wound treatment and are known to be the leading cause of burn infections (Nedeljković, Tiodorović, Kocić, Cirić, Milojković, and Waisi