If the results are positive for a presence of free lambda light chains in the urine and an absence of monoclonal gammopathy, this is indicative of Amyloidosis. A subcutaneous fat aspirate will be performed and sent to the pathology lab for confirmatory tests. A pathologist will review the abdominal fat biopsy and if the aspirate is negative, then an invasive biopsy of the suspected organ must be performed to confirm or exclude the disease. *If negative, the tissue biopsy will *The tissue will be stained with Congo Red. This will stain a type of protein called an amyloid, found in patients with amyloidosis. A patient’s diagnosis relies on pathological examination of Congo red-positive amyloid deposits, which present as typical apple-green birefringence under polarized light using immunofluorescence (Desport, et al., 2012). The presence of the green color under a polarizing microscope confirms that the patient is positive for amyloids, indicating
If the results are positive for a presence of free lambda light chains in the urine and an absence of monoclonal gammopathy, this is indicative of Amyloidosis. A subcutaneous fat aspirate will be performed and sent to the pathology lab for confirmatory tests. A pathologist will review the abdominal fat biopsy and if the aspirate is negative, then an invasive biopsy of the suspected organ must be performed to confirm or exclude the disease. *If negative, the tissue biopsy will *The tissue will be stained with Congo Red. This will stain a type of protein called an amyloid, found in patients with amyloidosis. A patient’s diagnosis relies on pathological examination of Congo red-positive amyloid deposits, which present as typical apple-green birefringence under polarized light using immunofluorescence (Desport, et al., 2012). The presence of the green color under a polarizing microscope confirms that the patient is positive for amyloids, indicating