Mr. Metzner is clearly showing an alteration of ADH (antidiuretic hormone). Having a deficient amount of ADH, means your urine cannot be concentrated and you would need to drink an incredibly large amount of water in order for your kidneys to filter out what they need to. Due to the fact that Mr. Metzner is deficient in ADH, he will have to urinate frequently. This could be a sign or symptom of many diseases or disorders; one being diabetes insipidus. Other possible causes of deficient ADH are drinking alcohol and the use of diuretics. Drinking alcohol inhibits the activity of ADH causing increased urination, dehydration, and a hangover. Diuretics, prescribed for blood pressure, inhibit ADH by lowering blood volume and blood pressure causing
