INTRODUCTION
The breast comprises of glands called lobules that produce milk and thin tubes called ducts that carry the milk from the lobules to the nipple. Breast tissue also contains fat and connective tissue, lymph nodes, and blood vessels.
Breast cancer usually starts off in the inner lining of milk ducts or the lobules that supply them with milk. A malignant tumor can spread to other parts of the body. Most prevalent breast cancer is Ductal carcinoma, which begins in the cells of the ducts. Breast cancer can also begin in the cells of the lobules. Invasive breast …show more content…
It has been hypothesized that such a link might be related to the effect of glucose on insulin levels in the body. The glucose absorbed into the blood stream after the digestion of carbohydrates stimulates the release of the hormone insulin from the pancreas. Insulin affects the action of other hormones in the body including insulin-like growth factor (IGF) and possibly estrogen. A number of studies have suggested that higher blood levels of IGF may be linked to an increased risk of premenopausal but not postmenopausal breast cancer risk. Increased levels of estrogen in the body have been clearly linked to increased breast cancer risk.
In vivo studies have also shown increase in proliferation of normal and cancerous breast cells due to increased insulin levels. So far, studies of the relationship of insulin and its metabolic products to breast cancer have been inconsistent, but this area still remains gray due to lack of substantial …show more content…
It depends on the amount of glucose present in the diet compared to the total carbohydrate content of the food composition. Various food products such as meat and dairy products have high glycemic index and hence lead to high level of glucose and also glutamine in the blood circulation. As the presence of high glutamine receptors on the cancer cells shows the role of glutamine in inducing the proliferation of cells and also blocking these receptors reduces the formation of tumor in the body. Also, high glycemic index food leads to high blood sugar levels and hence the body produces more insulin but due to the uncontrolled proliferation the cell cyclins and protein degradation peptides are blocked and hence the cell death is blocked leading to IR( Insulin Resistance) like conditions which also leads to generation of Reactive oxygen species; and, which in turn leads to affect the pituitary hormones such as estrogen and hence adding up in the effect of breast cancer proliferation whereas on the other side Mediterrian diet which includes extra virgin oil possessing oleic acid and antioxidants leads to cell death and hence reducing the occurrence of cell proliferation in the patients suffering from breast