Children usually contain less body fat, so less drugs can dissovle into adipose tissue. As a result, the drug concentration in the bloodstream of children is higher than that in the adults even with the same dosage. More drugs distribute to the tissues in children, so the dosage of children should be lower to prevent overdose. In this case, Prince applied a high dosage of Fentanyl, but his fat tissues are too little for Fentanyl to dissolve into it. Hiigh concentration of Fentanyl stays in the bloodstream and enters body tissues. This results in Fentanyl
Children usually contain less body fat, so less drugs can dissovle into adipose tissue. As a result, the drug concentration in the bloodstream of children is higher than that in the adults even with the same dosage. More drugs distribute to the tissues in children, so the dosage of children should be lower to prevent overdose. In this case, Prince applied a high dosage of Fentanyl, but his fat tissues are too little for Fentanyl to dissolve into it. Hiigh concentration of Fentanyl stays in the bloodstream and enters body tissues. This results in Fentanyl