Fexofenadine
is a non-sedating, long-acting second genaration antihistamine, it is a metabolite of terfenadine and a piperidine type antihistamine.
7 placebo-controlled, double-blind were recognized that have assessed the efficacy of fexofenadine.in chronic urticaria (table 1). the large number of patients included (a total of 1894 subjects) and the number of studies done makes it in the treatment of chronic urticaria the best studied second-generation antihistamine. Fexofenadine has been examined in an assortment of doses for chronic urticaria. Examining fexofenadine 20 mg, 60 mg, 180 mg, and 240 mg, 2 large multicenter studies found dosages of twice daily 60mg and greater to be better than twice daily 20mg dosage.…