Cholinergic crisis results from an overdose of acetylcholinesterase inhibitors causing profound weakness due to continuous depolarization of the postsynaptic membrane, which in turn results in a depolarizing type of neuromuscular blockade; cholinergic crisis may develop secondary to drug overdose, such as anticholinesterase
Cholinergic crisis results from an overdose of acetylcholinesterase inhibitors causing profound weakness due to continuous depolarization of the postsynaptic membrane, which in turn results in a depolarizing type of neuromuscular blockade; cholinergic crisis may develop secondary to drug overdose, such as anticholinesterase